diff --git a/invesalius/control.py b/invesalius/control.py
index a7cbf5c..e5aab88 100755
--- a/invesalius/control.py
+++ b/invesalius/control.py
@@ -317,8 +317,6 @@ class Controller():
     def LoadProject(self):
         proj = prj.Project()
 
-        mask_index = len(proj.mask_dict) -1
-
         const.THRESHOLD_OUTVALUE = proj.threshold_range[0]
         const.THRESHOLD_INVALUE = proj.threshold_range[1]
         const.WINDOW_LEVEL[_('Default')] = (proj.window, proj.level)
@@ -339,7 +337,9 @@ class Controller():
         ps.Publisher().sendMessage('Show content panel')
         ps.Publisher().sendMessage('Update AUI')
         ps.Publisher().sendMessage('Load slice plane')
-        ps.Publisher().sendMessage('Change mask selected', mask_index)
+        if len(proj.mask_dict):
+            mask_index = len(proj.mask_dict) -1
+            ps.Publisher().sendMessage('Show mask', (mask_index, True))
         ps.Publisher().sendMessage('End busy cursor')
 
     def CreateAnalyzeProject(self, imagedata):
diff --git a/invesalius/data/slice_.py b/invesalius/data/slice_.py
index 7921f50..7b24943 100644
--- a/invesalius/data/slice_.py
+++ b/invesalius/data/slice_.py
@@ -338,7 +338,7 @@ class Slice(object):
         # This condition is not necessary in Linux, only under mac and windows
         # because combobox event is binded when the same item is selected again.
         #if index != self.current_mask.index:
-        if self.current_mask and self.blend_filter:
+        if self.current_mask and self.blend_filter and index > -1:
             proj = Project()
             future_mask = proj.GetMask(index)
             future_mask.is_shown = True
diff --git a/invesalius/gui/data_notebook.py b/invesalius/gui/data_notebook.py
index 82a8d4c..4090445 100644
--- a/invesalius/gui/data_notebook.py
+++ b/invesalius/gui/data_notebook.py
@@ -96,7 +96,11 @@ class MasksListCtrlPanel(wx.ListCtrl, listmix.TextEditMixin):
     def OnChangeCurrentMask(self, pubsub_evt):
 
         mask_index = pubsub_evt.data
-        self.SetItemImage(mask_index, 1)
+        try:
+            self.SetItemImage(mask_index, 1)
+        except wx._core.PyAssertionError:
+            #in SetItem(): invalid item index in SetItem
+            pass
         for key in self.mask_list_index.keys():
             if key != mask_index:
                 self.SetItemImage(key, 0)
--
libgit2 0.21.2