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docs/user_guide_en_source/capa.tex
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2 2  
3 3 \begin{flushright}
4 4  
5   -\flushright \scalebox{2.5}{\sffamily{\textbf{Software InVesalius}}}
  5 +\flushright \scalebox{2.5}{\sffamily{\textbf{InVesalius}}}
6 6 \par
7 7 \vspace{180pt}
8 8 \scalebox{2.8}{\sffamily User Guide}
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docs/user_guide_en_source/intro.tex
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1 1 \chapter{Introduction}
2   -%Este manual tem como objetivo mostrar o uso das ferramentas
3   -%do InVesalius e também apresentar alguns conceitos para facilitar
4   -%a utilização do software.
5 2  
6   -This manual aims to show the use of InVesalius tools and also present some concepts to facilitate the use of the software.
  3 +This manual aims to guide end users in the application of InVesalius tools and also presents some concepts to facilitate the use of the software.
7 4  
8   -%O InVesalius é um software para auxiliar o profissional
9   -%de saúde no diagnóstico e no planejamento cirúrgico. Cabe
10   -%ressaltar, porém, que todo software no contexto de diagnóstico é
11   -%totalmente suplementar, pois todo e qualquer ato cometido é de
12   -%inteira responsabilidade do profissional de saúde.
13   -
14   -InVesalius is a software that is designed to assist health professionals on diagnosis and surgical planning. It should be noted, however, that all software in the diagnostic context is fully supplementary, and each and every act committed is the responsibility of health professionals.
  5 +InVesalius is software that is designed to assist health professionals on diagnosis and surgical planning. It should be noted, however, that all software in the diagnostic context is fully supplementary, and each and every act committed is the responsibility of health professionals.
15 6  
16   -%Além da medicina, é possível utilizar o software em outras áreas, como
17   -%arqueologia, veterinária, ou mesmo em aplicações industriais.
18   -%Como requisito básico, basta que as imagens a serem analisadas
19   -%estejam no padrão DICOM (\textsl{Digital Imaging Communications in Medicine}).
20   -%Até o presente momento, o InVesalius reconstrói
21   -%imagens provindas de tomógrafos e de aparelhos de ressonância magnética.
22   -%Para operar o software, basta ter conhecimentos básicos de
23   -%informática. Noções básicas sobre imagens médicas podem contribuir para o
24   -%melhor entendimento das operações.
25   -
26   -In addition to the medicine, you can use the software in other areas such as archaeology, medicine, dentistry, veterinary, or even in industrial applications. As a basic requirement, the images to be analyzed are in DICOM (Digital Imaging Communications in Medicine). To date, InVesalius reconstructs images stemmed from CT scanners and MRI machines. To operate the software, one needs to posses basic computer skills cos. Understanding medical images can help to form a better understanding of the operations.
27   -
28   -%\section{Conceitos importantes}
29   -\section{Important Concepts}
  7 +In addition to medicine, InVesalius can be utilized in other areas such as archeology, medicine, dentistry, veterinary, or even in industrial applications. As a basic requirement, the images to be analyzed are in DICOM (Digital Imaging Communications in Medicine). To date, InVesalius reconstructs images stemmed from CT scanners and MRI machines. To operate the software, basic computer literacy is essential. Understanding medical images can help to form a better understanding of the operations.
30 8  
31   -%Nesta seção, discutiremos alguns conceitos necessários para melhor
32   -%entendimento e operação do software.
33   -In this section, we discuss some concepts necessary to better understanding of and operation of the software.
  9 +\section{Important Concepts}
34 10  
35   -\subsection{DICOM (\textit{Digital Image Communications in Medicine})}
36   -%DICOM é um padrão relativo à transmissão, ao armazenamento e
37   -%ao tratamento de imagens médicas. O padrão prevê diversas modalidades de imagens médicas,
38   -%como imagens provindas de equipamentos de tomografia computadorizada, ressonância magnética,
39   -%ultrassom, eletrocardiograma, entre outras.
  11 +Detailed in this section are a list of concepts essential to better understand and operate the software.
40 12  
41   -DICOM is a standard on the transmission, storage and treatment of medical images. The standard provides various types of medical images, such as images emanating from computed tomography equipment, magnetic resonance, ultrasound, electrocardiogram, among others.
  13 +\subsection{DICOM (\textit{Digital Image Communications in Medicine})}
42 14  
43   -%Uma imagem DICOM é composta por 2 itens principais, uma matriz contendo os pixels da
44   -%imagem e um conjunto de meta-informações. Essas informações contêm, por exemplo, o nome
45   -%do paciente, a modalidade da imagem e a posição da imagem em relação ao espaço (no caso
46   -%de tomografia e ressonância).
  15 +DICOM is a standard the transmission, storage and treatment of medical images. The standard encompasses various origins of medical images, such as images emanating from computed tomography (CT) equipment, magnetic resonance, ultrasound, and electrocardiogram, among others.
47 16  
48 17 A DICOM image consists of two main components, namely, an array containing the pixels of the image and a set of meta-information. This information includes, but is not limited to, patient name, mode image and the image position in relation to the space (in the case of CT and MRI).
49 18  
50 19 \subsection{Computed Tomography - Medical}
51   -%A tomografia computadorizada indica a radiodensidade dos tecidos, isto é, a média de
52   -%absorção de raios-X pelos tecidos. A radiodensiade é traduzida para a imagem em níveis
53   -%de cinza em uma escala chamada \textit{Hounsfield}, nome dado em homenagem a Godfrey
54   -%Newbold Hounsfield, um dos criadores da primeira máquina de tomografia computadorizada.
55 20  
56   -Computed tomography indicates the radiodensity of tissues, i.e., the average X-ray absorption by the tissues. The radiodensiade is translated into an image in gray levels, called the \textit{Hounsfield} scale, named after Godfrey Newbold Hounsfield, one of the creators of the first CT scan machine.
  21 +Computed tomography indicates the radiodensity of tissues, i.e., the average X-ray absorption by the tissues. The radiodensity reading is translated into an image gray levels, called the Hounsfield scale, named Godfrey Newbold Hounsfield, one of the creators of the first CT scan.
57 22  
58 23 \begin{figure}[!htb]
59 24 \centering
... ... @@ -61,26 +26,13 @@ Computed tomography indicates the radiodensity of tissues, i.e., the average X-r
61 26 \caption{Medical CT scanner - www.toshibamedical.com.br}
62 27 \end{figure}
63 28  
64   -%Nos aparelhos mais modernos, com um emissor de radiação e um banco de
65   -%sensores (também chamados de canais, variando de 2 até 256), que circundam o paciente
66   -%enquanto a maca é movimentada, formando uma espiral, é possível gerar uma
67   -%grande quantidade de imagens, simultaneamente, com pouca emissão de raios-X.
  29 +Most modern CT scanning appliances are equipped with a radiation emitter and a sensor bank (with channels ranging from 2 to 256), which circle the patient while the stretcher is moved, forming a spiral. This generates a large number of images simultaneously, with little emission of X-rays.
68 30  
69   -In the most modern appliances, with a radiation emitter and a sensor bank (also called channels, ranging from 2 to 256), which circumvent the patient while the stretcher is moved, forming a spiral, it is possible to generate a large number of images simultaneously, with little emission of X-rays.
70   -
71   -%\subsubsection{Escala de Hounsfield}
72 31 \subsubsection{Hounsfield Scale}
73 32  
74   -%Como citado na seção anterior, as imagens de tomografia computadorizada
75   -%são geradas em níveis de cinza, os quais são depois traduzidos na escala
76   -%de Hounsfield (HU). Os tons mais claros representam tecidos mais densos, e
77   -%os mais escuros, tecidos menos densos, como a pele e o cérebro.
78   -As mentioned in the previous section, the CT images are generated in gray levels, which are then translated in the range of Hounsfield (HU). The lighter shades represent denser fabrics, and the darker, less dense tissue such as skin and brain.
79   -
80   -%A tabela \ref{tab:escala_hounsfield} apresenta alguns materiais e seus
81   -%respectivos valores em HU (\textit{Hounsfield Unit}).
  33 +As mentioned in the previous section, the CT images are generated in gray levels, expressed in Hounsfield (HU), wherein lighter shades represent denser matters, and the darker, less dense matter such as skin and brain tissues.
82 34  
83   -Table~\ref{tab:escala_hounsfield} presents some materials and their repective values in HU (\textit{Hounsfield Unit}).
  35 +Table~\ref{tab:escala_hounsfield} presents some materials and their respective values in Hounsfield Units (HU).
84 36  
85 37 \begin{table}[h]
86 38 \centering
... ... @@ -104,11 +56,7 @@ Bone & 400 or more\\
104 56  
105 57 \subsection{Computed Tomography - Dental (CBCT)}
106 58  
107   -%A tomografia computadorizada odontológica comumente trabalha com menos emissão
108   -%de radiação se comparada à tomografia computadorizada médica e, em consequência,
109   -%torna possível visualizar mais detalhes de regiões delicadas, como a cortical alveolar.
110   -
111   -The dental CT commonly works with less radiation emission if compared to medical CT, and therefore makes it possible to view more details of delicate regions such as alveolar cortical.
  59 +The dental CT commonly works with less radiation emission compared to medical CT, and therefore makes it possible to view more details of delicate regions such as alveolar cortical.
112 60  
113 61 \begin{figure}[!htb]
114 62 \centering
... ... @@ -116,40 +64,15 @@ The dental CT commonly works with less radiation emission if compared to medical
116 64 \caption{Detal tomography - www.kavo.com.br}
117 65 \end{figure}
118 66  
119   -%A aquisição das imagens é feita com o paciente na vertical (ao contrário da tomografia médica,
120   -%em que o paciente fica na horizontal). Um emissor e um sensor de raios-X circundam o crânio
121   -%do paciente, formando um arco de $180^\circ$ ou $360^\circ$. As imagens geradas pelo tomógrafo
122   -%podem ser interpretadas como um volume com o crânio do paciente imerso. Esse volume é "fatiado"
123   -%pelo software do aparelho, podendo-se gerar imagens com espaçamentos diferentes ou outros
124   -%tipos de imagens, como a visão panorâmica da região de interesse.
125   -
126   -Image acquisition is performed with the patient in the vertical (as opposed to medical tomography, the patient is horizontal). A transmitter and a sensor X-ray surround the patient's skull, forming an arc of $180^\circ$ or $360^\circ$. The images generated by the scanner can be interpreted as a volume with the skull immersed patient. This volume is "sliced" by the instrument software, being able to generate images with different spacing or other types of images, such as the panoramic view of the region of interest.
  67 +Image acquisition is performed with the patient positioned vertically (as opposed to medical tomography in which the patient is horizontal). A transmitter X-ray surround the patient's skull, forming an arc of $180^\circ$ or $360^\circ$. The images generated are compiled as a volume of the patient's skull. This volume is then "sliced" by the software into individual layers, being able to generate images with different spacing or fields of view, such as a panoramic view of the region of interest.
127 68  
128   -%As imagens adquiridas por tomógrafos odontológicos costumam exigir um maior pós-processamento
129   -%quando é necessário separar (segmentar) determinadas estruturas usando outros softwares como
130   -%o InVesalius. Isso ocorre porque, normalmente, essas imagens possuem mais níveis de cinza que
131   -%a escala de Hounsfield, o que torna o uso de padrões de segmentação \textit{(presets)} menos
132   -%eficiente. Outra característica bastante comum nas imagens provindas de tomógrafos
133   -%odontológicos é a alta presença de ruídos do tipo \textit{speckle} e a presença de outros
134   -%ruídos normalmente causados por uso de próteses de amálgama pelo paciente.
135   -
136   -The images acquired by dental scanners often require more post processing when it is necessary to separate (segmental) certain structures using other software such as InVesalius. This is because, typically, these images have more gray levels than the study shut Hounsfield, which makes the use of segmentation patterns (preset) less efficient. Another very common feature in the images of provincial dental CT scanners is the high presence of speckle noise type and the presence of other noise typically caused by the use of amalgam prosthesis by the patient.
  69 +The images acquired by dental scanners often require more post processing when it is necessary to separate (segmental) certain structures using other software such as InVesalius. This is because, typically, these images have more gray levels than, which makes use of segmentation patterns (preset) less. Another very common feature in the images of provincial dental CT scanners is the high presence of speckle noise and other forms of noise typically caused by the presence of amalgam prosthetics.
137 70  
138 71 \subsection{Magnetic Resonance Imaging - MRI}
139 72  
140   -%A ressonância magnética é um exame realizado sem o uso de radiação ionizante. Em vez disso,
141   -%é utilizado um forte campo magnético para alinhar os átomos de algum elemento presente em
142   -%nosso corpo, comumente o hidrogênio. Após o alinhamento, são disparadas ondas de rádio, e os
143   -%átomos são excitados. Os sensores medem o tempo que os átomos de hidrogênio demoram para se
144   -%alinhar novamente. Com isso, é possível determinar qual é o tipo de tecido, pois tecidos
145   -%diferentes apresentam quantidades diferentes de átomos de hidrogênio.
146   -
147   -MRI is an examination performed without the use of ionizing radiation. Instead, it used a strong magnetic field to align the atoms of any element present in our body, commonly the nio hydrogenated. After alignment, radio waves are triggered, and atoms are excited. The sensors measure the time that the hydrogen atoms democratic ram to align again. This makes it possible to determine what kind of fabric, because different tissues have different amounts of hydrogen atoms.
  73 +MRI is an examination performed without the use of ionizing radiation. Instead, it use a strong magnetic field to align the atoms of any element present in our body, most commonly hydrogen. After alignment, radio waves are triggered to excite atoms. The sensors measure the time that the hydrogen atoms take to realign. This makes it possible to distinguish between different tissues, as different types possess different quantities of hydrogen atoms.
148 74  
149   -%Para evitar interferências e melhorar a qualidade do sinal de radiofrequência, além de o
150   -%paciente ficar dentro do equipamento, é colocada uma bobina na região de interesse.
151   -
152   -To avoid interference and improve the quality of the radiofrequency signal, and the patient get inside the machine, it is placed a coil in the region of interest.
  75 +To avoid interference and improve the quality of the radiofrequency signal, the patient is placed inside a narrow tube encompassed by the coil and scanning unit.
153 76  
154 77 \begin{figure}[!htb]
155 78 \centering
... ... @@ -167,59 +90,45 @@ To avoid interference and improve the quality of the radiofrequency signal, and
167 90 \label{sec:neuronavegador_intro}
168 91  
169 92 Neuronavigation is a technique that allows tracking and localization of surgical instruments relative to neuronal
170   -structures through computer visualization. In addition, neuronavigation systems have been pointed out as a fundamental
171   -tool to aid surgical planinng and to increase the accuracy of experiments in neuroscience, such as transcranial magnetic
172   -stimulation (TMS), electroencephalography (EEG), magnetoencephalography (MEG) and near-infrared spectroscopy (NIRS).
  93 +structures through computer visualization. In addition, neuronavigation systems a fundamental tool to aid surgical plan and to increase the accuracy of experiments in neuroscience, such as transcranial magnetic stimulation (TMS), electroencephalography (EEG), magnetoencephalography (MEG) and near-infrared spectroscopy (NIRS).
173 94 Despite the vast field of applications, the use of neuronavigation in research centers is limited by its high cost.
174   -InVesalius Navigator offers users a low-cost, open-source alternative to commercial navigation systems. In this sense,
175   -it is possible to use specific tools for neuronavigation and still have the possibility of developing features on demand.
176   -The software for neuronavigation is distributed in an executable version compatible with Windows 7, 8 and 10 operating
177   -system. The chapter~\ref{sec:neuronavegador} goes into details of all features of neuronavigation in InVesalius.
178   -
  95 +InVesalius Navigator offers users a low-cost, open-source alternative to commercial neuronavigation systems. In this sense, it is possible to use specific tools for
  96 +neuronavigation and still have the possibility of developing features on demand. The software for neuronavigation is distributed in an executable version compatible with Windows 7, 8 and 10 operating system. The chapter~\ref{sec:neuronavegador} goes into details of all features of neuronavigation in InVesalius.
179 97  
180   -%\section{Recursos necessários}
181 98 \section{Resources needed}
182 99  
183   -%O InVesalius é projetado para executar em computadores pessoais, como
184   -%\textit{desktops} e \textit{notebooks}. Atualmente, ele é compatível com
185   -%os seguintes sistemas operacionais:\\
186   -The InVesalius is designed to run on personal computers, such as desktops and notebooks. Currently, it is compatible with the following operating systems:\\
187   -- MS-Windows (Windows 7, 8 e 10)\\
188   -- GNU/Linux (Ubuntu, Mandriva, Fedora)\\
189   -- Apple Mac OS X
190   -
191   -%O desempenho do InVesalius depende, principalmente, da quantidade de fatias
192   -%reconstruídas (imagens abertas pelo software), da quantidade de memória RAM
193   -%disponível, da frequência do processador e da arquitetura do sistema operacional
194   -%(32 \textit{bits} ou 64 \textit{bits}).
195   -
196   -The performance of InVesalius depends mainly on the amount of reconstructed slices (images offered by the software), the amount of memory available RAM, the processor frequency and operating system architecture (32-bit or 64-bit).
197   -
198   -%Vale ressaltar, como regra geral, que quanto maior a quantidade de memória RAM
199   -%disponível no sistema, maior será o número de fatias que podem ser abertas
200   -%simultaneamente para um dado estudo. Por exemplo, com 1 GB de memória disponível,
201   -%pode-se abrir cerca de 300 fatias com resolução de 512x512 \textit{pixels}.
202   -%Já com 4 GB de memória, pode-se abrir em torno de 1000 imagens com a mesma
203   -%resolução.
204   -It is noteworthy, as a general rule, the greater the amount of memory available RAM on the system, the greater the number of slices that can be opened simultaneously for a given study. For example, with 1 GB of available memory, it can open about 300 slices with a resolution of 512x512 pixels. Now with 4GB of memory, it can be opened around 1000 images at the same resolution.
205   -
206   -
207   -%\subsection{Configurações mínimas}
  100 +InVesalius is designed to run on personal computers, such as desktops and notebooks. Currently, it is compatible with the following operating systems:
  101 +
  102 +\begin{itemize}
  103 + \item Microsoft Windows (Windows 7, 8, 10)
  104 + \item GNU/Linux (Ubuntu, Mandriva, Fedora)
  105 + \item Apple Mac OS X
  106 +\end{itemize}
  107 +
  108 +The performance of InVesalius depends mainly on the amount of reconstructed slices (images offered by the software), the amount of random access memory (RAM) available, the processor clock rate \& frequency, and operating system architecture (32-bit or 64-bit).
  109 +
  110 +It is important to note that, as a general rule, the greater the amount of RAM available on the system, the greater the number of slices that can be opened simultaneously. For example, with 1 GB of available memory, it can open about 300 slices with a resolution of 512x512 pixels. With 4 GB of memory, around 1000 images can be opened simultaneously at the same resolution.
  111 +
208 112 \subsection{Minimum settings}
209   -32 \textit{bits} Operating System\\
210   -Intel Pentium 4 or equivalent with frequency 1,5 GHz\\
211   -1 GB RAM\\
212   -80 GB hard disk\\
213   -Graphics card with 64 MB de memória\\
214   -Video resolution of 1024x768 \textit{pixels}
  113 +
  114 +\begin{itemize}
  115 + \item 32-bit Operating System
  116 + \item Intel Pentium 4 or equivalent 1.5 GHz
  117 + \item 1 GB RAM
  118 + \item 10 GB available hard disk space
  119 + \item Graphics card with 64 MB memory
  120 + \item Video resolution of 1024x768 pixels
  121 +\end{itemize}
215 122  
216 123  
217   -%\subsection{Configurações recomendadas}
218 124 \subsection{Recommended settings}
219   -64 \textit{bits} Operating System\\
220   -Intel Core 2 Duo processor or equivalent, with a frequency of 2.5 GHz\\
221   -4GB of RAM\\
222   -180 GB of hard disk\\
223   -NVidia or ATI graphics card with 128 MB of memory\\
224   -Video resolution of 1024x768 \textit{pixels}
  125 +\begin{itemize}
  126 + \item 64-bit Operating System
  127 + \item Intel Core 2 Duo processor or equivalent 2.5 GHz
  128 + \item 4GB of RAM
  129 + \item 20 GB available hard disk space
  130 + \item NVidia or ATI graphics card with 128 MB of memory
  131 + \item Video resolution of 1024x768 pixels
  132 +\end{itemize}
  133 +
225 134  
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docs/user_guide_en_source/resumo.tex
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8 8  
9 9 \onehalfspacing
10 10  
11   -%InVesalius é um software público para a área de saúde que realiza análise e segmentação de
12   -%modelos anatômicos virtuais, possibilitando a confecção de modelos físicos com o auxílio da
13   -%prototipagem rápida.
14   -%A partir de imagens em duas dimensões (2D) obtidas por meio de equipamentos de Tomografia
15   -%Computadorizada (TC) ou Ressonância Magnética (RM), o programa permite criar modelos
16   -%virtuais em três dimensões (3D) correspondentes às estruturas anatômicas dos pacientes em
17   -%acompanhamento médico.
18   -
19   -InVesalius is a public health software that performs analysis and segmentation of
  11 +InVesalius is public health software that performs analysis and segmentation of
20 12 Virtual anatomical models, enabling the creation of physical models with the aid of
21 13 rapid prototyping (3D printing).
22   -From two-dimensional (2D) images obtained by means of Tomography Computerized (CT) or Magnetic Resonance (MRI), the program allows to create
23   -three-dimensional (3D) anatomical structures corresponding the patients in medical follow-up.
24   -
25   -%O nome InVesalius é uma homenagem ao médico belga Andreas Vesalius (1514-1564),
26   -%considerado o "pai da anatomia moderna".
27   -%O software InVesalius é desenvolvido pelo CTI (Centro de Tecnologia da Informação Renato
28   -%Archer), unidade do Ministério da Ciência e Tecnologia (MCT), desde 2001. Inicialmente, apenas
29   -%o programa de instalação era distribuído gratuitamente. A partir de novembro de 2007,
30   -%o InVesalius foi disponibilizado como software livre no Portal do Software Público
31   -%(\href{http://www.softwarepublico.gov.br}{www.softwarepublico.gov.br}), consolidando comunidades de usuários e de desenvolvedores.
32   -%Trata-se de uma ferramenta simples, livre e gratuita,
33   -%robusta, multiplataforma, com comandos em Português, com funções claras e diretas, de fácil
34   -%manuseio e rápida quando executada em microcomputador PC.
  14 +From two-dimensional (2D) images obtained through Computed Tomography (CT) or Magnetic Resonance Imaging (MRI), the program allows users to create
  15 +three-dimensional (3D) anatomical representations of patients for further medical use.
35 16  
36   -InVesalius name is a tribute to the Belgian doctor Andreas Vesalius (1514-1564),
37   -considered the "father of modern anatomy".
  17 +InVesalius is named in honour of the Belgian doctor Andreas Vesalius (1514-1564), widely
  18 +considered the father of modern anatomy.
38 19 InVesalius software is developed by CTI (Center for Information Technology Center Renato
39 20 Archer), a unit of the Brazilian Ministry of Science and Technology (MCT), since 2001. Initially, only
40   -the installation program was distributed as freeware. On the November 2007
41   -InVesalius was made available as free software and open source in the Public Software Portal
42   -(\href{http://www.softwarepublico.gov.br}{www.softwarepublico.gov.br}), consolidating communities of users and developers.
43   -It is a simple, easy to use, robust, cross-platform and free tool.
44   -
45   -%O uso das tecnologias de visualização e análise tridimensional de imagens médicas, integradas
46   -%ou não a prototipagem rápida, auxiliam o cirurgião no diagnóstico de patologias e permitem que
47   -%seja realizado um planejamento cirúrgico detalhado, simulando com antecedência intervenções
48   -%complexas, que podem envolver, por exemplo, alto grau de deformidade facial ou a colocação
49   -%de próteses.
  21 +the installation program was distributed as freeware. In November 2007
  22 +InVesalius was made fully available as free software and open source via the Public Software Portal
  23 +(\href{http://www.softwarepublico.gov.br}{www.softwarepublico.gov.br}), allowing for communities of users and developers to connect.
  24 +InVesalius is, in short, a simple yet robust, free cross-platform tool that is easy to use.
50 25  
51   -The use of visualization technologies and three-dimensional analysis of medical images , perhaps integrated with rapid prototyping, assists the surgeon in diagnosing pathologies and a detailed surgical planning, simulating complex interventions in advance, which may involve, for example, a high degree of facial deformity or of prosthetics.
52 26  
53   -%O InVesalius tem demonstrado grande versatilidade e vem contribuindo com diversas áreas,
54   -%dentre as quais medicina, odontologia, veterinária, arqueologia e engenharia.
  27 +The use of visualization technologies and three-dimensional analysis of medical images, when combined with rapid prototyping (3D printing), assists the surgeon in diagnosing pathologies and a detailed surgical planning and simulation of complex process in advance, which may involve, for example, a high degree of facial deformity or integration of prosthetics.
55 28  
56   -InVesalius has demonstrated great versatility and has contributed to several areas,
57   -including medicine, dentistry, veterinary medicine, archeology and engineering.
  29 +InVesalius has demonstrated great versatility and has applications in different areas, including medicine, dentistry, veterinary medicine, archeology and engineering.
58 30  
59 31 -\noindent
  32 +\noindent
60 33 \ No newline at end of file
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docs/user_guide_en_source/user_guide_en.tex
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29 29 \graphicspath{{../user_guide_figures/}{../user_guide_figures/invesalius_screen/}{../user_guide_figures/icons/}}
30 30  
31 31 \author{Centro de Tecnologia da Informação Renato Archer}
32   -\title{Software InVesalius - User guide}
  32 +\title{InVesalius - User guide}
33 33 \date{}
34 34  
35 35 \begin{document}
... ...